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. 2020 Mar 9;11:1276. doi: 10.1038/s41467-020-14942-5

Fig. 1. Screening of P. simplex for steroid sensing aTFs.

Fig. 1

a–e Log2-fold change expression in response to each hormone relative to control. Each triangle is a gene (red = differentially expressed TF, black = non-differentially expressed TF, blue = gene with annotated sterol related function, green = differentially expressed other gene, gray = non-differentially expressed other gene). The Steroid Responsive Gene Island (SRGI) that is differentially expressed in response to PRG, ALD, and CRT is boxed in red. SRTF1 and SRTF2 are two steroid responsive TFs. f Zoomed in view of SRGI. Yellow peaks are experimentally validated binding sites for SRTF1. g SRGI region around SRTF1. h SRTF1 palindromic binding site upstream of SRTF1 gene. RNA-seq data are deposited in the Gene Expression Omnibus with accession number GSE141603.