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. 2020 Mar 9;10:88. doi: 10.1038/s41398-020-0769-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a FDR Q value for SNP association with LOAD conditional with SNP association for MDD. Plot is made for the results from the full genome. b FDR Q value for SNP association with MDD association conditional with SNP association for LOAD. Plot is made for results from the full genome. c FDR Q value for SNP association with LOAD association conditional with SNP association for MDD. Plot is made for the results, excluding SNPs in the APOE-associated region. d FDR Q value for SNP association with MDD association conditional with SNP association for LOAD. Plot is made for the results, excluding SNPs in the APOE-associated region. e conjunction conditional FDR Q value for SNP association with LOAD conditional with SNP association for MDD. Plot is made for the results, including SNPs in the APOE-associated region. f Conjunction conditional FDR Q value for SNP association with MDD conditional with SNP association for LOAD. Plot is made for the results, excluding the APOE-associated region. For panels a–d, genome-wide significant line (red) is drawn at –log₁₀(5 × 10⁻⁸), suggestive line (blue) is drawn at −log₁₀(1 × 10⁻⁵); for panels e and f, genome-wide significant line (red) is drawn at –log₁₀(0.05), suggestive line (blue) is drawn at –log₁₀(0.1).