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. 2020 Feb 20;52(2):281–292. doi: 10.1038/s12276-020-0389-x

Fig. 1. Results obtained after ligand-based pharmacophore screening with LigandScout.

Fig. 1

a 2D diagram of matching hydrophobic pharmacophoric features between (yellow spheres) migrastatin and imipramine. b 3D alignment of migrastatin (blue skeleton) and imipramine (yellow skeleton).