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. 2020 Mar 9;10:4287. doi: 10.1038/s41598-020-61257-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Segmentation of the substantia nigra and red nucleus in the second experiment, as in Fig. 2a, overlaid on T1-weighted (top) and proton density-weighted (bottom row) images from the ICBM atlas. In T1-weighted images, the iron-rich region of the substantia nigra is slightly hypointense (SNhr). In proton density-weighted images, it is enclosed in a slightly hyperintense area. The color scale refers to the percent of individuals in which the voxel was classified as belonging to the hypointense region in the T2*-weighted EPI images. MNI coordinates, abbreviations as in Fig. 2a.