Table 1.

Half Maximal Inhibitory Concentration (IC₅₀) of Erlotinib Alone and in Combination with miRNAs, after 24 and 48 h of Treatment

Treatment	IC50
	24 h	48 h
Erlotinib	21.42 ± 1.10	14.41 ± 2.10
NC miRNA and erlotinib	20.49 ± 1.17#	13.25 ± 1.30#
miRNA-125a-5p and erlotinib	9.87 ± 2.15*	6.54 ± 0.99*

IC₅₀ values were determined by sigmoidal dose-response (variable slope) model using GraphPad Prism software. Data expressed as the mean±SD (n=3). *p<0.05 relative to the corresponding erlotinib group; #p>0.05 versus corresponding erlotinib.