Table 4.
Genotypic and Allelic Frequency Distribution of rs1063320 among African Ethnics
| Population | TNZ | LWK | MKK | YRI | ASW | AFR | |
|---|---|---|---|---|---|---|---|
| N | 139 | 89 | 142 | 108 | 49 | 661 | |
| Genotype frequency (%): | CC | 33.9 | 23.6 | 8.5 | 12 | 10.2 | 13.8 |
| CG | 46.4 | 53.9 | 40.8 | 46.3 | 57.1 | 48.3 | |
| GG | 19.7 | 22.5 | 50.7 | 41.7 | 32.7 | 38 | |
| p* | 0.104 | 0.001 | 0.001 | 0.002 | 0.001 | ||
| Allelic frequency: (%) | C | 57 | 50.6 | 28.9 | 35.2 | 38.8 | 37.9 |
| G | 43 | 49.4 | 71.1 | 64.8 | 61.2 | 62.1 | |
| p** | 0.18 | 0.001 | 0.001 | 0.002 | 0.001 | ||
| p*** | 0.588 | 0.529 | 1 | 1 | 0.231 | 0.563 |
Chi-square test integrated in HWE software was used for comparative analysis of genotypic and allelic frequencies distribution; p* and p**, p-values for genotypic and allelic frequencies distribution (respectively) comparison between respective population and Tanzanian (TNZ); ***p, Fisher’s test p-value for deviation of genotypic distribution from HWE. Association was significant if p<0.05.