Table 2.
Clinicopathological Characteristics versus Low and High COX-2 Scores
| Variables | Characteristics | Total 100 (100.0%) |
Low COX-2
41 (41.0%) |
High COX-2 59 (59.0%) |
p-value |
|---|---|---|---|---|---|
| IDO Score | Low | 24 (24.0) | 16 (66.7) | 8 (33.3) | 0.004* |
| High | 76 (76.0) | 25 (32.9) | 51 (67.1) | ||
| Total | 100 (100.0) | 41 (41.0) | 59 (59.0) | ||
| Estrogen receptor | Negative | 69 (69.0) | 35 (50.7) | 34 (49.3) | 0.003* |
| Positive | 31 (31.0) | 6 (19.4) | 25 (80.6) | ||
| Total | 100 (100.0) | 41 (41.0) | 59 (59.0) | ||
| Progesterone receptor | Negative | 74 (74.0) | 37 (50.0) | 37 (50.0) | 0.002* |
| Positive | 26 (26.0) | 4 (15.4) | 22 (84.6) | ||
| Total | 100 (100.0) | 41 (41.0) | 59 (59.0) | ||
| HER2–neu receptor | Negative | 74 (74.0) | 33 (44.6) | 41 (55.4) | 0.22 |
| Positive | 26 (26.0) | 8 (30.8) | 18 (69.2) | ||
| Total | 100 (100.0) | 41 (41.0) | 59 (59.0) | ||
| Metastasis | Negative | 38 (38.0) | 19 (50.0) | 19 (50.0) | 0.21 |
| Positive | 49 (49.0) | 18 (36.7) | 31 (63.3) | ||
| Total | 87 (87.0) | 37 (42.5) | 50 (57.5) | ||
| Grade | II | 36 (36.0) | 10 (27.8) | 26 (72.2) | 0.02* |
| III | 56 (56.0) | 29 (51.8) | 27 (48.2) | ||
| Total | 92 (92.0) | 39 (42.4) | 53 (57.6) | ||
| Nodes | N0 | 37 (37.0) | 18 (48.6) | 19 (51.4) | 0.17 |
| N1 | 24 (24.0) | 7 (29.2) | 17 (70.8) | ||
| N2 | 13 (13.0) | 4 (30.8) | 9 (69.2) | ||
| N3 | 13 (13.0) | 8 (61.5) | 5 (38.5) | ||
| Total | 87 (87.0) | 37 (42.5) | 50 (57.5) | ||
| Histology | Ductal | 91 (91.0) | 38 (41.8) | 53 (58.2) | 0.82 |
| Mammary | 6 (6.0) | 2 (33.3) | 4 (66.7) | ||
| Lobular | 2 (2.0) | 1 (50.0) | 1 (50.0) | ||
| Metaplastic | 1 (1.0) | 0 (0.0) | 1 (100.0) | ||
| Total | 100 (100.0) | 41 (41.0) | 59 (59.0) | ||
| Tumor Size | T1 | 7 (7.0) | 2 (28.6) | 5 (71.4) | 0.34 |
| T2 | 49 (49.0) | 18 (36.7) | 31 (63.3) | ||
| T3 | 8 (8.0) | 5 (62.5) | 3 (37.5) | ||
| Total | 64 (64.0) | 25 (39.1) | 39 (60.9) |
*values indicate statistical significance p< 0.05; IDO, Indoleamine 2,3-dioxygenase