Table 3.

Risk Factors of COX-2 High Expression

Variables	Characteristics	Univariable analysis odds ratio (95% CI), p-value	Multivariable analysis odds ratio (95% CI), p-value
Age (years)	Mean ± SD	1.04 (1.00-1.10), 0.02	1.04 (1.00-1.10), 0.05*
Estrogen receptor	Negative	Ref	Ref
	Positive	4.30 (1.60-11.76), 0.01	5.62 (1.80-17.84), 0.002*
IDO Score	Low	Ref	Ref
	High	4.10 (1.54-10.81), 0.01	6.51 (2.00-21.20), 0.001*

*values indicate statistical significance p< 0.05; IDO, Indoleamine 2,3-dioxygenase