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. 2020 Mar 9;10:4341. doi: 10.1038/s41598-020-61281-y

Table 2.

Identified clusters of deaths by prescription opioid overdose for Ohio 2010–2017, and aggregations by hotspots (HS) and Non-Hotspots (NHS) areas. Confidence Intervals (CI) at 95% are included for averaged relative risks (RR) and RR temporal change of mortality rate of prescription opioid overdose.

Cluster Radius (Km) Estimated population in 2017 Total death cases (All years) Total death cases (2017) Mortality rate in 2017 Cases per 100.000 hab. RR (2017) Mean [95% CI] RR temporal changea (%) Mean [95% CI]
1 12.64 188,097 771 353 187.66 3.61 [2.33–4.89] +48.94 [+25.72–+72.16]
2 17.09 152,828 647 211 138.06 2.20 [1.76–2.64] +9.63 [−10.69–+30.22]
3 9.20 165,470 607 216 130.54 2.94 [1.83–4.05] +20.58 [−0.98–+42.16]
4 8.92 181,154 598 194 107.09 2.61 [1.90–3.31] +7.87 [−2.55–+18.30]
5 8.87 127,772 437 105 82.18 2.58 [1.90–3.26] +17.88 [+4.55–+31.20]
6 7.14 112,734 386 121 107.33 2.45 [0.63–4.26] –16.99 [−33.85––0.12]
7 15.66 69,965 254 82 117.20 1.78 [1.20–2.36] +1.77 [−9.77–+13.31]
8 13.93 125,693 381 128 101.84 1.78 [1.37–2.18] +1.18 [−7.76–+10.12]
9 24.34 49,170 173 46 93.55 2.41 [1.51–3.31] −2.10 [−12.66–+8.47]
10 6.44 120,373 315 78 64.80 1.71 [1.26–2.17] −9.07 [–19.49–+1.36]
11 10.96 8,672 37 7 80.72 3.04 [0.77–5.28] −1.65 [−15.58–+12.28]
12 25.83 61,884 163 41 66.25 1.28 [0.76–1.81] −2.84 [−25.20–19.53]
TOTAL HS 161.01 1,363,811 4,769 1,582 116.00 2.42 [2.15–2.68] +10.17 [+4.82–+15.51]
TOTAL NHS 5,166,333 7,021 2,092 40.49 0.80 [0.77–0.84] −3.20 [−4.10–−2.31]
TOTAL 6,530,144 11,790 3,674 56.26 1.01 [0.95–1.06] −1.51 [–2.57–−0.45]

aRR temporal change 2010–2017 was defined as: (RR¯lastsemester2017RR¯firstsemester2010)RR¯firstsemester2010.