Table 1.
Patient characteristics, and immunohistochemistry scores of MCL1, BCL-XL, BCL-2, ASCL1, NEUROD1, YAP1, and POU2F3.
| Patient number | Age at diagnosis | Sex | Smoking history (pack year) | TNM stage | H-scores (0–300) | Tumor proportion scores (%) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCL1 | BCL-XL | BCL-2 | ASCL1 | NEUROD1 | YAP1 | POU2F3 | MCL1 | BCL-XL | BCL-2 | |||||
| 1 | 64 | M | 45 | pT4N1M0 | 127.80 | 57.44 | 9.39 | 41.22 | 22.29 | 0.66 | 125.73 | 29.6 | 3.6 | 0.2 |
| 2 | 67 | F | 58.75 | pT1aN0M0 | 144.07 | 119.87 | 31.93 | 228.87 | 0.05 | 7.02 | 37.99 | 39.1 | 27.1 | 2.0 |
| 3 | 74 | F | 50 | pT3N1M0 | 234.44 | 154.43 | 48.74 | 255.36 | 202.52 | 2.62 | 13.79 | 93.3 | 52.8 | 2.6 |
| 4 | 70 | M | 50 | pT1N1M0 | 209.41 | 204.52 | 51.01 | 212.49 | 145.21 | 4.33 | 22.36 | 84.5 | 78.4 | 2.6 |
| 5 | 45 | M | 30 | pT3N1M0 | 200.00 | 125.44 | 0.08 | 0.00 | 1.12 | 6.45 | 16.05 | 86.9 | 32.7 | 0.0 |
| 6 | 65 | M | 45 | pT3N0M0 | 213.52 | 113.61 | 7.66 | 36.79 | 0.21 | 5.63 | 100.41 | 86.4 | 32.0 | 0.5 |
| 7 | 68 | M | NA | pTXNXM1 | 230.12 | 151.69 | 117.09 | 135.78 | 61.22 | 25.41 | 63.18 | 93.6 | 50.5 | 35.8 |
| 8 | 74 | F | 23 | pT1aN0M0 | 221.33 | 64.68 | 107.08 | 34.59 | 4.54 | 3.65 | 29.15 | 90.7 | 4.4 | 25.1 |
| 9 | 51 | M | 60 | pT2N1M0 | 233.89 | 147.46 | 124.14 | 215.73 | 5.93 | 14.25 | 87.95 | 93.1 | 47.4 | 35.7 |
| 10 | 71 | M | 45 | pT2aN0M0 | 234.79 | 178.09 | 32.44 | 100.74 | 0.38 | 3.85 | 176.43 | 97.2 | 65.6 | 2.5 |
| 11 | 71 | F | 0 | pT2aN2M0 | 216.02 | 159.07 | 157.64 | 117.08 | 5.05 | 43.43 | 66.86 | 93.2 | 54.1 | 54.3 |
| 12 | 87 | M | 60 | pT2aN0M0 | 222.88 | 176.25 | 96.24 | 23.39 | 1.80 | 1.39 | 88.79 | 88.9 | 63.2 | 23.5 |
| 13 | 61 | M | 34 | pT3N0M0 | 252.90 | 118.12 | 4.41 | 63.76 | 42.88 | 3.67 | 185.68 | 96.5 | 25.5 | 0.1 |
| 14 | 62 | F | 42 | pT1aN0M0 | 207.50 | 141.07 | 3.00 | 0.15 | 26.41 | 85.48 | 196.88 | 87.4 | 42.4 | 0.2 |
| 15 | 72 | M | 67.5 | pT3N0M0 | 171.11 | 9.56 | 0.00 | 0.040 | 2.37 | 4.22 | 158.13 | 61.4 | 0.1 | 0.0 |
| 16 | 70 | M | 90 | pT2aN0M0 | 282.23 | 195.83 | 218.90 | 240.22 | 171.37 | 60.73 | 128.52 | 99.0 | 74.7 | 75.6 |
| 17 | 79 | M | 45 | pT1bN0M0 | 170.21 | 81.09 | 0.11 | 0.35 | 0.01 | 1.25 | 54.13 | 66.5 | 8.1 | 0.0 |
| 18 | 59 | M | 80 | pT1aN0M0 | 224.04 | 72.22 | 15.75 | 87.11 | 24.48 | 25.33 | 91.73 | 92.8 | 6.8 | 0.8 |
| 19 | 81 | F | 45 | pT1aN0M0 | 219.89 | 110.47 | 221.06 | 0.02 | 10.96 | 9.75 | 107.39 | 88.4 | 22.4 | 78.4 |
| 20 | 74 | F | 0 | pT1cN1M0 | 218.4 | 188.02 | 22.44 | 174.60 | 3.57 | 8.23 | 68.91 | 87.8 | 68.6 | 2.8 |
| 21 | 53 | M | 33 | pT1N1M0 | 148.62 | 144.69 | 2.04 | 115.74 | 13.18 | 63.72 | 102.61 | 41.4 | 45.8 | 0.1 |
| 22 | 72 | F | 50 | pT3aN0M0 | 242.82 | 93.47 | 10.72 | 17.55 | 233.10 | 159.19 | 138.08 | 87.8 | 18.7 | 0.5 |
| 23 | 79 | M | 60 | pT1bN0M0 | 251.67 | 79.58 | 84.18 | 98.43 | 0.43 | 27.02 | 159.21 | 95.1 | 13.0 | 19.0 |
| 24 | 74 | F | 24 | pT2aN0M0 | 188.44 | 5.34 | 7.43 | 15.52 | 22.07 | 24.66 | 70.65 | 75.5 | 0.0 | 0.2 |
| 25 | 73 | M | 47 | pT2aN0M0 | 273.66 | 211.42 | 10.19 | 195.58 | 0.36 | 26.31 | 83.02 | 93.7 | 76.9 | 0.8 |