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. 2020 Mar 3;11:163. doi: 10.3389/fphar.2020.00163

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Copyright © 2020 Huang, Kang, Narayanan, DiPietro, Cooper, Gajendrareddy and Ravindran

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lineage-specific differentiation of human mesenchymal stem cells (HMSCs) in vivo: Confocal micrographs representing immunohistochemical staining for the presence of lineage specific proteins in the tissue explants from the subcutaneous implantation of HMSCs with and without respective control and lineage specific EVs. The red boxed images represent lineage specific protein expression. In all images, blue represents DAPI nuclear staining and red or green represents the immunolabeled protein. Scale bar represents 20 µm in all images.