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Immunohistochemical analysis of platelet interaction with amyloid plaques in the brain of APP-PS1 mice. Brain sections from APP-PS1 mice (n = 1/gender) were co-stained for platelets (green) and Thioflavin S (yellow). DAPI (blue) was used as nucleus stain. Representative confocal images were 3D modeled for co-localization analysis. In APP-PS1 mice, CD41+ platelets were not associated with Thioflavin S+ amyloid plaques.
