Table 2.
Effect of HML on blood biochemistry in tumor-bearing mice. (mean ± SD, n = 5).
| Group | Dose (mg/kg) | Blood biochemical parameters |
|||||
|---|---|---|---|---|---|---|---|
| ALT (U/L) | AST (U/L) | ALP (U/L) | BUN (mmol/L) | CREA (μmol/L) | UA (μmol/L) | ||
| Non-tumor | – | 68.27 ± 10.05 | 176.10 ± 34.80 | 113.42 ± 36.63 | 5.98 ± 1.87 | 19.07 ± 2.14 | 160.43 ± 31.66 |
| DMSO | – | 64.85 ± 19.59 | 180.26 ± 41.33 | 125.68 ± 29.87 | 7.49 ± 1.22 | 20.58 ± 1.58 | 180.58 ± 48.23 |
| HML | 10 | 72.92 ± 13.85 | 160.58 ± 38.48 | 132.64 ± 31.58 | 6.72 ± 2.06 | 22.07 ± 1.84 | 167.91 ± 28.59 |
| HML | 20 | 74.58 ± 22.64 | 218.11 ± 44.92 | 122.58 ± 34.59 | 7.45 ± 1.59 | 17.86 ± 2.35 | 203.59 ± 38.04 |
| CDDP | 5 | 103.92 ± 26.25 | 257.27 ± 37.34a | 102.32 ± 42.59 | 16.21 ± 3.56a | 46.59 ± 10.59a | 302.57 ± 52.72a |
a
P < 0.05, compared to non-tumor group.