Fig. 4.

TMT protein analysis reveals subtle changes in ALDH2^−/− mice. (A) Volcano plot comparing results of TMT proteomics from hippocampi of WT and ALDH2^−/− mice treated daily with 10 mg/kg HH i.p for 2 weeks. (B) Bar chart showing fold change (log2) for differentially expressed proteins with significance decreasing from top to bottom. (C) Table describing the function of all proteins differentially expressed. Volcano plots: vertical line shows .05 P-value, while horizontal line depicts 1.5 fold change. All studies were performed on 14 month old mice.