Table 2.
SciRAP quality assessment of the included studies.
| Study and year | Purpose and aim | Endpoints | Test compound | Vehicle | Ethical statement | Test system | Administration of test compound | Methods | Statistics | Data | Discussion | Other | overall quality |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Almstruup. K et al. (2002) | fulfilled | fulfilled | not fulfilled | not determined | not determined | not fulfilled | not fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fair |
| Altawash et al. (2017) | fulfilled | partially fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | good |
| Bajgai et al. (2011) | partially fulfilled | partially fulfilled | not fulfilled | fulfilled | not determined | fulfilled | fulfilled | fulfilled | partially fulfilled | fulfilled | fulfilled | fulfilled | fair |
| Campbell et al. (1993) | fulfilled | fulfilled | fulfilled | fulfilled | not determined | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | good |
| Dhawan et al. (2002) | fulfilled | fulfilled | fulfilled | not determined | not determined | partially fulfilled | fulfilled | fulfilled | partially fulfilled | fulfilled | fulfilled | fulfilled | fair |
| Edmunds et al. (2005) | fulfilled | fulfilled | fulfilled | fulfilled | not determined | fulfilled | fulfilled | fulfilled | partially fulfilled | fulfilled | fulfilled | fulfilled | good |
| Gambelunghe et al. (2003) | fulfilled | fulfilled | not fulfilled | fulfilled | not determined | partially fulfilled | fulfilled | fulfilled | not fulfilled | fulfilled | fulfilled | fulfilled | fair |
| Jeong et al. (1999) | fulfilled | fulfilled | partially fulfilled | not determined | not determined | fulfilled | fulfilled | partially fulfilled | not fulfilled | fulfilled | fulfilled | fulfilled | good |
| Kao et al. (1998) | fulfilled | fulfilled | fulfilled | fulfilled | not determined | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | good |
| Kellis et al. (1994) | fulfilled | fulfilled | not fulfilled | not fulfilled | not determined | partially fulfilled | partially fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fair |
| Lannone et al. (2018) | fulfilled | fulfilled | fulfilled | fulfilled | not determined | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | good |
| Le Bail et al. (2000) | fulfilled | fulfilled | partially fulfilled | fulfilled | not determined | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | good |
| Nega Ta and Thomas Walle (2007) | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | good |
| Pelissero et al. (1996) | fulfilled | fulfilled | fulfilled | fulfilled | not determined | fulfilled | fulfilled | fulfilled | not fulfilled | fulfilled | fulfilled | fulfilled | good |
| Saarinen at al. (2001) | fulfilled | fulfilled | fulfilled | fulfilled | not determined | fulfilled | fulfilled | fulfilled | not fulfilled | fulfilled | fulfilled | fulfilled | good |
| Sanderson et al. (2004) | fulfilled | fulfilled | fulfilled | fulfilled | not determined | fulfilled | fulfilled | fulfilled | not fulfilled | fulfilled | fulfilled | fulfilled | good |
| Sassa Deapaeng et al. (2017) | fulfilled | fulfilled | fulfilled | fulfilled | not determined | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | good |
| Van meeuwen et al. (2007) | fulfilled | fulfilled | fulfilled | fulfilled | not determined | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | good |
| Van meeuwen et al. (2008) | fulfilled | fulfilled | fulfilled | fulfilled | not determined | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | fulfilled | good |