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. 2020 Mar 7;6(3):e03526. doi: 10.1016/j.heliyon.2020.e03526

Table 1.

IP3 and DAG production and degradation parameters.

Parameters Definition Values Reference
v4 Maximal rate of IP3 and DAG formation by PLC 5.0 μM s−1 Scaled from [27]
v5 Maximal rate of IP3 dephosphorylation 12.5 μM s−1 Scaled from [27]
v6 Maximal rate of IP3 phosphorylation 0.9 μM s−1 Scaled from [27]
K5 IP3 dissociation constant 6.0 μM Scaled from [27]
K6 IP3 dissociation constant 0.1 μM Scaled from [27]
K7 Ca2+ dissociation constant 1.0 μM Scaled from [27]
H Hill coefficient 1 [27]
v8 DAG degradation rate 1.0 s−1 Estimated