PUNI
|
Uniporter Ca2+ permeability |
2.776× 10−14 s−1
|
Estimated |
αm
|
Mitochondrial Ca2+ activity coefficient |
0.2 |
[89] |
αss
|
Subspace Ca2+ activity coefficient |
1.0 |
Fit to [26] |
Vnc
|
Na+-Ca2+ exchanger maximal velocity |
1.836 μM s−1
|
Estimated |
KNa
|
Na+-Ca2+ exchanger Na + affinity |
8.0 mM |
[90] |
KCa
|
Na+-Ca2+ exchanger Ca2+ affinity |
8 μM |
[90] |
Ψm
|
Mitochondrial membrane potential |
160 mV |
[91] |
[Na+]SS
|
Extramitochondrial Na+ concentration |
5.0 mM |
[32] |
[Na+]m
|
Mitochondrial Na+ concentration |
5.0 mM |
Estimated |
βCa
|
Ca2+ buffers in the mitochondria. |
0.01 |
[92] |