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. 2020 Mar 7;6(3):e03526. doi: 10.1016/j.heliyon.2020.e03526

Table 7.

–Membrane currents parameters.

Parameters Definition Values Reference
Emax Maximum conductance for Ca2+-dependent K+ channel 0.8 nS [6, 29]
Kd Ca2+ dissociation constant for Ca2+-dependent K+ channel 0.45 μM [29]
gt Maximum conductance of the K+ channels 3.0 nS [6]
EK Reversal potential of K+ -84 mV [6, 95]
gCl Maximum conductance of the background current 0.07 nS Estimated
ECl Reversal potential for Cl- -33.0 mV [95]
gNa Maximum conductance of the Na + channels 3.0 nS Estimated
ENa Reversal potential of K+ -70 mV [6, 95]
Cm Membrane capacitance 2.5e-3 nF [94]
ECa Reversal potential of Ca2+ 60 mV [6, 95]
PcaL L-type Ca2+ channel permeability 0.3 x 10−7 cm2s−1 [32]
gTRPC3 Maximum conductance of TRPC3 channels 0.00195 nS Estimated
KDAG DAG binding constant for TRPC3 activation 2.0 μM Estimated
ETRPM4 TRPM4 reversal potential 0.2 mV [30]
gTRPM4 Maximum conductance of TRPM4 channels 1.2 nS Estimated
τxCa Hodgkin-Huxley time constant TRPM4 channel 30 s [30]