Table 1.

Desensitization protocol

Total dose	10 mg	Solution concentration	Total dose in each solution (mg)
Solution A	5 mL	0.04 mg/mL	0.2 mg
Solution B	5 mL	0.4 mg/mL	2 mg
Solution C	1 mL	20 mg/mL	20 mg

Step	Solution	Administered volume (mL)	Time (min)	Administered dose (mg)	Fold increase per step	Approximate cumulative dose (mg)
1	A	0.5	15	0.02	NA	0.02
2	A	1	15	0.04	X2	0.06
3	A	1.5	15	0.06	X1.5	0.12
4	A	2	15	0.08	x2	0.2
5	B	0.25	15	0.1	X1.2	0.3
6	B	0.5	15	0.2	X2	0.5
7	B	1	15	0.4	X2	0.9
8	B	1.5	15	0.6	X1.5	1.5
9	B	1.75	15	0.7	X1.5	2.2
10	C	0.05	15	1	X1.5	3.2
11	C	0.1	15	2	X2	4.2
12	C	0.1	15	2	N/A	6.2
13	C	0.2	120	4	X2	10.2