Table 3. Topics for future PGHD research.

Area for PGHD Research	Example research question
Methodology: topics that relate to advancing methods for analyzing and interpreting PGHD or validating measurement strategies	When can PGHD be used as a variable in risk prediction modeling?
	What are the methodology considerations for PGHD when data is censored or missing (not at random)?
	What methodologies are appropriate for estimating clinically importance differences for PGHD?
Care coordination: topics that relate to incorporating PGHD to inform healthcare delivery, inform treatment regimens, and clinical decision-support	How does activity tracking change function overtime for patients with chronic progressive conditions?
	Can PGHD support preventive medicine, and how?
	How do different telehealth/technology driven strategies leveraging PGHD compare in the delivery of care as compared to traditional clinic-based care?
Workflow and provider efficiency: topics that relate to team-based care, integration of PGHD into clinic workflow, use of PGHD to support workflow efficiency	What workflows best support the use/monitoring of PGHD in clinical care?
	How does inclusion of technology change the composition of the healthcare team (i.e., skillset needs)?
	How can technology-supported PGHD capture improve efficiency in clinical care?
Healthcare utilization: topics that relate to how PGHD impacts access to healthcare and decision-making regarding healthcare utilization	How does tracking PGHD inform patient decision-making to access or utilize healthcare services?
	What is the impact on utilization (i.e., readmission, LOS, medication utilization) for healthcare systems using PGHD to direct care?
	How does PGHD support value-based care models?
Patient engagement and patient centered care: topics that relate to patient activation, engagement with PGHD, patient-provider communication, and individualized care	How can incorporating PGHD improve patient satisfaction?

PGHD, patient-generated health data.