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ROS formation in pancreatic islets of Langerhans from the rat after exposure to TBT (10 μM), ES (1 μM), and TBT (10 μM) plus Es (1 μM). Values are expressed as mean ± SEM with a replication number, n = 4. ∗∗∗ significantly different from control at P-value < 0.001, # significantly different from TBT at P-value < 0.05, TBT: tributyltin, Es: β-estradiol, ROS: reactive oxygen species.
