Gurgan 1992.
Methods | Truly randomised (table of random numbers) Time of randomisation: after initial laparoscopic ovarian drilling 40 women randomised 1 woman declined treatment after the randomisation ‐ excluded from the analysis in the original study 6‐month follow up | |
Participants | Women with polycystic ovarian syndrome resistant to clomiphene who underwent laparoscopic ovarian laser drilling. Mean age 25.2 years (range 21‐31 years), mean duration of infertility 4.4 years. 33 women had primary and 7 had secondary infertility. Infertility work up consisted of semen analysis (normal in 36 men and mildly oligo‐asthenospermic in 4 men) and normal HSG. No exclusion criteria prior to randomisation stated. The trial was carried out in 1991 at the University of Hecettepi, Ankara, Turkey, recruitment taking 6 months. | |
Interventions | Postoperative second‐look laparoscopy and adhesiolysis 3‐4 weeks following surgery versus no second‐look laparoscopy | |
Outcomes | Outcomes of relevance to this review:
Total pregnancy rate (per woman)
Live birth plus ongoing pregnancy rate (per woman)
Ectopic pregnancy rate (per woman)
Method of diagnosis of pregnancy: serum beta hCG levels and real time ultrasound
Miscarriage rate (per intrauterine pregnancy) Other outcomes: Ovulation rate (per woman) Multiple pregnancy rate (per pregnancy) |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Low risk | Random number tables. |
Allocation concealment? | Low risk | Opaque envelopes. |
Blinding? All outcomes | Unclear risk | Not stated within text. |
Incomplete outcome data addressed? All outcomes | Low risk | |
Free of selective reporting? | Low risk | |
Free of other bias? | Low risk |