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. 2012 Dec 12;2012(12):CD001894. doi: 10.1002/14651858.CD001894.pub5

Elhelw 2005.

Methods Power calculation not reported 
 ITT not stated 
 Published as abstract only
Participants 74 women from Egypt undergoing ICSI only 
 Poor prognosis 
 Previous 2 implantation failures 
 Cryo‐thaw cycles only
Interventions Laser hatching (thinning to quarter) versus no hatching. AH done 1 hour before embryo transfer 
 AH: 37 women randomised, 121 embryos transferred 
 Control: 37 women randomised, 130 embryos transferred
Outcomes Implantation rate, clinical pregnancy rate
Notes No author contact as all details in article
No data re no. of embryo transfer
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not stated, no details
Allocation concealment (selection bias) High risk Not used
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Participant blinding unclear 
 Assessor blinding unclear
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk No details
Selective reporting (reporting bias) High risk Conference abstract only. No evidence of a full paper. Live birth not reported