Germond 2004.

Methods	Multicentre RCT
Participants	153 women in four European IVF centres aged between 20 and 45 years old, having at least one functional ovary, having normal FSH and prolactin levels, having no clinically significant findings within six months before starting treatment, and having a normal uterine cavity
Interventions	Laser assisted hatching using diode laser AH: 56 women undergoing their first cycle of frozen‐thawed embryos, 23 women who had a poor prognosis using fresh embryos Control: 53 women undergoing their first cycle of frozen‐thawed embryos, 21 women who had a poor prognosis using fresh embryos
Outcomes	Clinical pregnancies, live births, miscarriages and multiple pregnancies
Notes	Power calculation performed ITT not stated Published as full paper
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Women were randomised according to a randomisation list
Allocation concealment (selection bias)	Unclear risk	Not stated in the text
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Not stated in the text
Incomplete outcome data (attrition bias) All outcomes	Low risk	No evidence of attrition bias
Selective reporting (reporting bias)	Low risk	Live birth reported