Isiklar 1999.

Methods	Single centre randomised trial
Participants	44 women from Turkey undergoing IVF Mean age not stated
Interventions	AH (mechanical; complete zona breach; ? hours egg retrieval to AH; ? hours AH to transfer) versus no AH AH: 22 women randomised, 83 embryos transferred Control: 22 women randomised, 78 embryos transferred
Outcomes	Implantation, clinical pregnancy, multiple pregnancy
Notes	Attempted to contact author about this study No of embryos transferred AH 3.7 Control 3.5 Unclear if power calculation performed ITT analysis unclear Published as abstract
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Randomised on day three
Allocation concealment (selection bias)	Unclear risk	Allocation concealment unclear
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Participants not blinded or unclear Assessor not blinded or unclear
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	ITT analysis unclear
Selective reporting (reporting bias)	Unclear risk	This publication was in abstract form only, no full paper publication was identified. The authors do not report on live birth