Laffoon 1999.
| Methods | Single centre, randomised trial | |
| Participants | 56 women from North America aged less than 40 years undergoing IVF. Mean age not stated | |
| Interventions | AH (mechanical; complete zona breach; ? hours egg retrieval to AH; ? hours AH to transfer) versus no AH AH: 28 women randomised, embryos transferred not stated Control: 28 women randomised, embryos transferred not stated | |
| Outcomes | Clinical pregnancy | |
| Notes | Attempted to contact author about this study No. of embryos transferred not stated Unclear if power calculation performed ITT analysis unclear Published as abstract |
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| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Timing and method not stated |
| Allocation concealment (selection bias) | Unclear risk | Allocation concealment unclear |
| Blinding (performance bias and detection bias) All outcomes | Unclear risk | Participants not blinded or unclear Assessor not blinded or unclear |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | ITT analysis unclear |
| Selective reporting (reporting bias) | High risk | Published as a conference abstract. Unable to find a full paper publication. Live birth was not reported |