Skip to main content
. 2012 Dec 12;2012(12):CD001894. doi: 10.1002/14651858.CD001894.pub5

Laffoon 1999.

Methods Single centre, randomised trial
Participants 56 women from North America aged less than 40 years undergoing IVF. Mean age not stated
Interventions AH (mechanical; complete zona breach; ? hours egg retrieval to AH; ? hours AH to transfer) versus no AH 
 AH: 28 women randomised, embryos transferred not stated 
 Control: 28 women randomised, embryos transferred not stated
Outcomes Clinical pregnancy
Notes Attempted to contact author about this study
No. of embryos transferred not stated
Unclear if power calculation performed 
 ITT analysis unclear 
 Published as abstract
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Timing and method not stated
Allocation concealment (selection bias) Unclear risk Allocation concealment unclear
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Participants not blinded or unclear 
 Assessor not blinded or unclear
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk ITT analysis unclear
Selective reporting (reporting bias) High risk Published as a conference abstract. Unable to find a full paper publication. Live birth was not reported