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. 2012 Dec 12;2012(12):CD001894. doi: 10.1002/14651858.CD001894.pub5

Sagoskin 2007.

Methods Randomised trial
Participants 199 women from USA undergoing IVF or ICSI 
 Good prognosis group with only one previous implantation failure 
 Fresh embryo transfer cycles only
Interventions Laser hatching (breach with hole) 
 AH: 121 randomised, 118 analysed, 254 embryos; Control: 82 randomised, 81 analysed, 170 embryos
Outcomes Live birth, clinical pregnancy, miscarriage and multiple pregnancy rate
Notes No author contact as all details clearly stated in article
ET: AH 2.2 (0.4); Control 2.1 (0.3)
Power calculation not reported 
 Published as a full paper
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Treatment assignments were determined by a computer‐generated randomised series in a 2:1 ratio of treatments to controls
Allocation concealment (selection bias) Unclear risk Not stated within the text
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Not stated within the text
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk ITT unclear
Selective reporting (reporting bias) Low risk Live birth reported