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. 2012 Dec 12;2012(12):CD001894. doi: 10.1002/14651858.CD001894.pub5

Tucker 1993.

Methods Single centre, randomised trial
Participants 218 women from North America undergoing IVF (mean basal FSH: control group 9.0 (5.3); AH group 8.8 (3.7) IU/L) 
 Mean age: control group 34.2 (4.1); AH group 34.1 (4.8)
Interventions AH with acid tyrodes thinning to 1/4; 72 hours egg retrieval to AH; 1 to 3 hours AH to transfer) versus no AH 
 AH: 110 women randomised, 333 embryos transferred 
 Control: 108 women randomised, 312 embryos transferred
Outcomes Implantation, clinical pregnancy
Notes Attempted to contact author about this study, no reply received
ET: AH 2.9, Control 3.0
Unclear if power calculation performed 
 ITT analysis unclear 
 Published as full paper
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Randomisation stated, but method unclear or incorrect
Allocation concealment (selection bias) Unclear risk Unclear, no details
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Participants not blinded or unclear 
 Assessor not blinded or unclear
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk ITT analysis unclear
Selective reporting (reporting bias) High risk Original protocol not viewed but authors did not report on live birth