Tucker 1993.
| Methods | Single centre, randomised trial | |
| Participants | 218 women from North America undergoing IVF (mean basal FSH: control group 9.0 (5.3); AH group 8.8 (3.7) IU/L) Mean age: control group 34.2 (4.1); AH group 34.1 (4.8) | |
| Interventions | AH with acid tyrodes thinning to 1/4; 72 hours egg retrieval to AH; 1 to 3 hours AH to transfer) versus no AH AH: 110 women randomised, 333 embryos transferred Control: 108 women randomised, 312 embryos transferred | |
| Outcomes | Implantation, clinical pregnancy | |
| Notes | Attempted to contact author about this study, no reply received ET: AH 2.9, Control 3.0 Unclear if power calculation performed ITT analysis unclear Published as full paper |
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| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Randomisation stated, but method unclear or incorrect |
| Allocation concealment (selection bias) | Unclear risk | Unclear, no details |
| Blinding (performance bias and detection bias) All outcomes | Unclear risk | Participants not blinded or unclear Assessor not blinded or unclear |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | ITT analysis unclear |
| Selective reporting (reporting bias) | High risk | Original protocol not viewed but authors did not report on live birth |