Figure 1.

Example workflow using GAMer to construct a tetrahedral domain suitable for use with finite element simulations. (A) A segmented electron tomogram of a murine cardiac calcium release unit (CRU) from Cell Image Library: 3603 is shown here. (B) Stacks of contours from the traced model are shown here. (C) The conditioned surface mesh of the model is shown here. (D) The tetrahedralized domain that can be used for simulating cytosolic diffusion is shown here. Note that we have inverted the tetrahedralized domain to represent the free space surrounding the CRU geometry. Scale bars, 200 nm. To see this figure in color, go online.