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. 2019 Nov 27;19:371–383. doi: 10.1016/j.omtn.2019.11.020

Figure 5.

Figure 5

H51(+67)W Is Well Distributed to All Analyzed Tissues and Induces Exon 51 Skipping

(A) Quantification of H51(+67)W tcDNA in tissues from mice treated with 200 mg/kg/week of H51(+67)W for 12 weeks and analyzed 2 weeks after the last dose. (B) Exon 51 skipping levels were evaluated by qRT-PCR in treated mdx52 tissues, 2 weeks after the end of the 12-week treatment at 200 mg/kg/week. Results are expressed as mean ± SEM (n = 4). TA, tibialis anterior; Gas, gastrocnemius; Quad, quadriceps; Bi, biceps; Dia, diaphragm.