Table 1. Studies to date examining liver transplant in alcoholic hepatitis.
Author/year | Location of study | Study design | Sample size (AH) | Primary outcomes | 6 mo. survival |
---|---|---|---|---|---|
Van Thiel et al., 1995 (19) | USA | Retrospective | 64 | Acute cellular rejection rates after LT for ALD | N/A |
Shakil et al., 1997 (20) | USA | Retrospective | 9 | Graft survival and relapse after LT | 89% |
Wells et al., 2007 (15) | USA | Retrospective | 32 | Graft survival and relapse after LT | 96% |
Immordino et al., 2009 (21) | France | Retrospective | 8 | Relapse after LT | N/A |
Mathurin et al., 2011 (13) | France | Prospective | 26 | Graft survival | 77% |
Tomé et al., 2002 (22) | Spain | Retrospective | 36 | Graft survival and relapse after LT | 79% |
Singal et al., 2012 (23) | USA | Retrospective | 55 | Graft survival and patient mortality | 95% |
Hasanin et al., 2015 (18) | USA | Retrospective | 12 centers listed AH patients for LT | Graft survival | 93% |
Im et al., 2016 (24) | USA | Retrospective | 16 | Graft survival and relapse | 88% |
Lee et al., 2017 (25) | USA | Retrospective | 17 | Graft survival and relapse after LT | 100% |
Lee et al., 2018 (26) | USA | Retrospective | 147 | Mortality and relapse | 94% (1 year) |
Bangaru et al., 2018 (27) | USA | Retrospective | 23 performed LT for AH | Selection criteria consensus and graft survival | 73.9% |
Lee et al., 2019 (28) | USA | Retrospective | 147 | Patient survival and relapse to alcohol use | N/A |
AH, alcoholic hepatitis; LT, liver transplantation; ALD, alcohol-associated liver disease.