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. 2020 Apr 5;5:28. doi: 10.21037/tgh.2019.11.12

Table 3. Gastric EC classification.

Classification Structure Nuclei
EC1 (non-neoplastic) Regularly arranged glands with consistent pattern, well-preserved lumen Uniform pattern of small, round, poorly-stained nuclei with homogenous size
EC2 (adenoma) Recognizable glandular structure, more compact arrangement with lumen narrowing (slit-like lumen) Small, round, poorly-stained nuclei with pseudostratification
EC3 (cancer) Distortion and loss of glandular structure, no recognizable lumen Hyperchromatic, disarranged nuclei with heterogeneity in size and shape, significant swelling of the nuclei = "enlarged nuclear sign"

EC, endocytoscopy.