Table 3. Gastric EC classification.
| Classification | Structure | Nuclei |
|---|---|---|
| EC1 (non-neoplastic) | Regularly arranged glands with consistent pattern, well-preserved lumen | Uniform pattern of small, round, poorly-stained nuclei with homogenous size |
| EC2 (adenoma) | Recognizable glandular structure, more compact arrangement with lumen narrowing (slit-like lumen) | Small, round, poorly-stained nuclei with pseudostratification |
| EC3 (cancer) | Distortion and loss of glandular structure, no recognizable lumen | Hyperchromatic, disarranged nuclei with heterogeneity in size and shape, significant swelling of the nuclei = "enlarged nuclear sign" |
EC, endocytoscopy.