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. 2020 Apr 5;5:22. doi: 10.21037/tgh.2019.10.13

Table 1. Previous studies investigating the impact of preoperative SMI-defined sarcopenia on the postoperative outcomes in patients with gastric cancer.

Authors Country No. of patients, sarcopenia/total Muscle mass measurement method SMI cut-offs to define sarcopenia Significant impact of sarcopenia
Male Female Postoperative complications Survival
Fukuda et al. (37) Japan 21/99 (21%) BIA 8.87 6.42 Yes N/A
Wang et al. (16) China 32/255 (13%) CT 36.0 29.0 Yes N/A
Huang et al. (38) China 176/470 (37%) CT 40.8 34.9 Yes (only severe sarcopenia) N/A
Zhang et al. (39) China 24/156 (15%) CT 40.8 34.9 Yes N/A
Zhuang et al. (44) China 389/937 (42%) CT 40.8 34.9 Yes Yes
Nishigori et al. (30) Japan 76/177 (43%) CT 53.0 for BMI ≥25.0;
43.0 for BMI <25.0
41.0 N/A Yes
Kudou et al. (40) Japan 42/148 (28%) CT 53.0 for BMI ≥25.0;
43.0 for BMI <25.0
41.0 No Yes
Tegels et al. (41) Netherlands 86/152 (57%) CT 53.0 for BMI ≥25.0;
43.0 for BMI <25.0
41.0 No No
Sakurai et al. (42) Japan 142/569 (25%) CT 43.2 34.6 No Yes
Tamandl et al. (43) Austria 130/200 (65%) CT 55.0 39.0 N/A Yes

Severe sarcopenia was defined as both low muscle strength and low physical performance in addition to low muscle mass. BIA, bioelectrical impedance analysis; CT, computed tomography; SMI, skeletal muscle index (CT: cm2/m2, BIA: kg/ m2); BMI, body mass index (kg/m2); N/A, not applicable.