Kinetic Curves of SNIPRs Detecting Clinically Relevant Mutations, Related to Figures 4 and 5
(A-B) SNIPRs for detection of drug-resistance mutations to the HIV reverse transcriptase (RT).
(C) SNIPR for detection of the P. falciparum artemisinin-resistance mutation C580Y in the K13 propeller domain.
(D-G) SNIPRs for detection of BRCA1 and BRCA2 genetic mutations associated with breast cancer.
(A-G) For all panels, n = 3 technical replicates; bars represent arithmetic mean ± SD.