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. 2020 Mar 5;180(5):1018–1032.e16. doi: 10.1016/j.cell.2020.02.011

Figure S5.

Figure S5

Kinetic Curves of SNIPRs Detecting Clinically Relevant Mutations, Related to Figures 4 and 5

(A-B) SNIPRs for detection of drug-resistance mutations to the HIV reverse transcriptase (RT).

(C) SNIPR for detection of the P. falciparum artemisinin-resistance mutation C580Y in the K13 propeller domain.

(D-G) SNIPRs for detection of BRCA1 and BRCA2 genetic mutations associated with breast cancer.

(A-G) For all panels, n = 3 technical replicates; bars represent arithmetic mean ± SD.