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Mean pupil diameter (panel A), mean systolic pressure (panel B) and mean diastolic pressure (panel C) after administration of placebo oxycodone (0 mg) or active oxycodone (10 mg) on the sample session days (Day 1) in the active lorcaserin (10 mg BID; closed circles) versus the placebo lorcaserin (0 mg BID; open circles) condition. PBO lorcaserin vs active lorcaserin: *p<0.01, **p<0.001
