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Nkx2.5+ progenitors fail to segregate into cardiac and endothelial populations in lzr mutants. (A-H) ISH for nkx2.5:Kaede in WT and lzr embryos at 14 s, 16 s, 18 s and 20 s. Views are dorsal with anterior up. Brackets in E and G denote anterior (a) and posterior (p) nkx2.5:Kaede+ clusters. 14 s: WT (n=47), lzr (n=5); 16 s: WT (n=26), lzr (n=6); 18 s: WT (n=29), lzr (n=6); 20 s: WT (n=58), lzr (n=6). Scale bar: 100 µm.
