Table 3.

Comparisons of the RCDs in the superficial and deep retinal capillary layers among controls and TAO patients with and without DON

Layers	Regions	Control (C)	Non-DON (N)	DON (D)	P Value (C vs. N)	P Value (C vs. D)	P Value (N vs. D)
SRCL (%)	TAZ	63.7 ± 3.3	60.0 ± 3.5	59.8 ± 4.5	< 0.001	< 0.001	0.807
	C1	57.6 ± 12.9	48.5 ± 14.6	51.1 ± 11.6	0.003	0.033	0.382
	C2	63.0 ± 5.6	60.6 ± 5.8	60.8 ± 5.2	0.069	0.092	0.869
	C3	64.0 ± 4.5	61.0 ± 4.3	61.2 ± 5.5	0.008	0.011	0.867
	C4	64.4 ± 3.7	61.4 ± 4.0	60.3 ± 5.3	0.003	< 0.001	0.326
	C5	64.8 ± 3.1	60.8 ± 3.8	60.9 ± 5.0	< 0.001	< 0.001	0.899
	C6	64.2 ± 2.9	61.4 ± 3.6	60.0 ± 4.4	0.001	< 0.001	0.127
	S	63.4 ± 3.9	60.3 ± 4.3	60.0 ± 5.3	0.004	0.001	0.789
	T	64.0 ± 3.5	61.2 ± 4.2	60.3 ± 5.0	0.005	< 0.001	0.385
	I	63.7 ± 3.6	59.7 ± 4.0	59.5 ± 5.6	< 0.001	< 0.001	0.857
	N	63.6 ± 4.3	59.0 ± 4.0	59.5 ± 4.5	< 0.001	< 0.001	0.652
DRCL (%)	TAZ	73.9 ± 4.8	70.2 ± 4.4	66.4 ± 7.7	0.007	< 0.001	0.006
	C1	40.6 ± 18.8	34.0 ± 16.2	29.7 ± 15.3	0.096	0.006	0.277
	C2	71.6 ± 8.5	66.7 ± 8.4	61.3 ± 12.4	0.039	< 0.001	0.020
	C3	78.3 ± 4.1	75.2 ± 4.3	71.9 ± 7.5	0.016	< 0.001	0.013
	C4	78.4 ± 4.0	75.9 ± 3.6	72.3 ± 7.4	0.045	< 0.001	0.004
	C5	77.8 ± 3.6	74.4 ± 3.9	71.3 ± 7.7	0.007	< 0.001	0.017
	C6	76.5 ± 4.2	72.9 ± 4.1	68.9 ± 8.1	0.009	< 0.001	0.004
	S	75.0 ± 4.6	71.2 ± 4.1	68.0 ± 8.1	0.008	< 0.001	0.020
	T	73.4 ± 4.7	69.4 ± 5.1	65.1 ± 9.2	0.011	< 0.001	0.007
	I	75.0 ± 4.9	71.5 ± 4.9	67.7 ± 7.0	0.009	< 0.001	0.005
	N	72.4 ± 5.7	68.8 ± 4.6	64.8 ± 7.9	0.017	< 0.001	0.007

RCD = retinal capillary density; TAO = thyroid-associated ophthalmopathy; DON = dysthyroid optic neuropathy; Control (C) = control subjects; Non-DON (N) = TAO patients without DON; DON (D) = TAO patients with DON; SRCL = superficial retinal capillary layer; DRCL = deep retinal capillary layer; C = central region; TAZ = total annular zone; C1~C6 = six annular zones; S = superior sector; T = temporal sector; I = inferior sector; N = nasal sector. Bold P-value represents < 0.01