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. 2020 Mar 10;7:16. doi: 10.1186/s40662-020-00180-9

Table 4.

ROC Curve Analysis of RCDs in the Retinal Capillary Layers and GCC Thickness in TAO Patients with DON

GCC + SRCL GCC + DRCL
Cut off Cut off
Regions AUC GCC (μm) RCD (%) Sensitivity (%) Specificity (%) AUC GCC (μm) RCD (%) Sensitivity (%) Specificity (%)
TAZ-C6 Total 0.85 83.2 64.6 79 84 0.86 83.2 79.5 89 66
S-C6 0.86 79.3 66.9 82 82 0.89 86.2 79.5 89 76
T-C6 0.83 92.8 60.2 74 89 0.84 95.4 68.6 66 89
I-C6 0.83 107.8 61.0 82 76 0.86 124.8 66.4 79 79
N-C6 0.85 95.7 61.0 87 76 0.88 80.7 78.6 87 76

RCD = retinal capillary density; GCC = ganglion cell complex; TAO = thyroid-associated ophthalmopathy; DON = dysthyroid optic neuropathy; SRCL = superficial retinal capillary layer; DRCL = deep retinal capillary layer; AUC = areas under the ROC curve; TAZ = total annular zone; S = superior sector; T = temporal sector; I = inferior sector; N = nasal sector