Table 5.
Comparison of means of each variable in quartile groups for urate levels in participants with diabetes
| 1st quartile Urate: 0.8–4.7 mg/dl |
2nd quartile Urate: 4.8–5.5 mg/dl |
3rd quartile Urate: 5.6–6.4 mg/dl |
4th quartile Urate: 6.5–12.9 mg/dl |
|
|---|---|---|---|---|
| WHtR | ||||
| Univariate | 0.514 (0.507–0.521) | 0.524 (0.515–0.532) | 0.522 (0.515–0.529) | 0.533 (0.525–0.541)* |
| Multivariate | 0.515 (0.507–0.522) | 0.523 (0.516–0.531) | 0.522 (0.515–0.530) | 0.532 (0.524–0.540)* |
| Systolic blood pressure (mmHg) | ||||
| Univariate | 132.6 (130.1–135.2) | 134.3 (131.9–136.7) | 133.4 (131.2–135.6)** | 134.5 (132.1–136.9)** |
| Multivariate | 134.2 (131.9–136.5) | 134.4 (132.2–136.6) | 133.3 (131.2–135.4) | 133.0 (130.6–135.3) |
| Diastolic blood pressure (mmHg) | ||||
| Univariate | 79.9 (78.1–81.7) | 80.5 (79.0–81.9) | 80.5 (79.0–81.9) | 83.1 (81.4–84.9) |
| Multivariate | 81.1 (79.6–82.7) | 80.7 (79.2–82.2) | 80.4 (79.0–81.8) | 81.8 (80.2–83.3) |
| log (triglycerides [mg/dl]) | ||||
| Univariate | 2.02 (1.98–2.06) | 2.09 (2.05–2.12) | 2.12 (2.08–2.15)* | 2.16 (2.12–2.20)** |
| Multivariate | 2.05 (2.01–2.08) | 2.09 (2.05–2.12) | 2.12 (2.08–2.15)* | 2.13 (2.09–2.17)* |
| HDL cholesterol (mg/dl) | ||||
| Univariate | 55.9 (53.6–58.2) | 51.6 (49.8–53.5)* | 51.9 (50.2–53.6)* | 52.1 (50.2–54.1) |
| Multivariate | 55.4 (53.6–57.2) | 52.0 (50.2–53.7) | 51.6 (50.0–53.3)* | 52.6 (50.7–54.5) |
| Hemoglobin A1c (%) | ||||
| Univariate | 7.85 (7.59–8.10) | 7.38 (7.19–7.57)* | 7.24 (7.07–7.41)** | 7.11 (6.92–7.31)** |
| Multivariate | 7.90 (7.70–8.10) | 7.39 (7.20–7.58)** | 7.25 (7.06–7.43)** | 7.04 (6.84–7.24)** |
Means with their 95% confidence intervals for each variable are shown. The range of urate levels in each quartile group is shown in the table. In multivariate analysis, adjusted odds ratios were estimated using age and histories of smoking, alcohol drinking and regular exercise as other explanatory variables. BMI was adjusted in analysis for variables except for WHtR. In addition, a history of medication therapy for hypertension, dyslipidemia or diabetes was used as an explanatory variable in multivariate analysis for systolic and diastolic blood pressure, triglycerides, HDL cholesterol, and hemoglobin A1c
Asterisks denote significant differences from the 1st quartile (* p < 0.05; ** p < 0.01)