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. 2020 Mar 10;21:220. doi: 10.1186/s12864-020-6649-2

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© The Author(s). 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Dynamic differential expression of circRNAs in goat skeletal muscle. a-d QPCR (Bar chart, blue) and RNA-seq expression (Line chart, orange) validation of the indicated goat skeletal muscle circRNAs. e Number of differentially expressed goat skeletal muscle circRNAs (SDECs) determined under stringent conditions (|log2^FoldChange | > 2 and P- adj value < 0.01) showing up- (red) or down- (blue) regulation during development. Orange: total number of differentially expressed genes between two stages. f SDEC abundance heat maps in the seven development stages of goat skeletal muscle. g H&E staining of paraffin sections for the seven development stages of goat skeletal muscle