Table 2.
Deregulated circRNA chosen for qPCR validation
Regulation | CircRNA | CircRNA type | FC (abs) | P-value | Chromosome position | Gene symbol | ||
---|---|---|---|---|---|---|---|---|
Up | hsa_circRNA_001359 | intronic | 7.0479384 | 0.002611197 | chr1 | 169663839 | 169664181 | SELL |
hsa_circRNA_103559 | exonic | 4.8769307 | 0.035206182 | chr3 | 196118683 | 196120490 | UBXN7 | |
hsa_circRNA_104220 | exonic | 4.8572966 | 0.026033314 | chr6 | 150092297 | 150094305 | PCMT1 | |
Down | hsa_circRNA_102488 | exonic | 2.7229035 | 8.17917E−05 | chr19 | 18684102 | 18684558 | UBA52 |
hsa_circRNA_104748 | exonic | 2.3292681 | 0.001448543 | chr9 | 20907148 | 20929595 | FOCAD |
CircRNA deregulated circRNA with greater intensity values in atherotrombotic stroke patients compared with cardioembolic; circRNA_type: the circRNAs are classified into 5 types: “exonic”, “intronic”, “antisense”, “sense overlapping” and “intergenic”; FC absolute ratio (no log scale) of normalized intensities between two conditions; p-value p-value calculated from unpaired t-test; Annotations, include chromosome position and Gene Symbol