Table 2.
Differentially Methylated Probes
| Fraction | Probe ID | Chr | Position | Gene | Gene feature | CpG island | Δβ (%) | P | Adj. P | chromHMM | Function |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 5mC | cg08753407 | 14 | 75,151,317 | AREL1 | Body | Open sea | −0.09 | 1.47E-07 | 3.60E-02 | 5_TxWk | Ubiquitination and antigen presentation |
| 5mC | cg03452759 | 2 | 31,467,215 | IGR | Open sea | 0.03 | 1.91E-07 | 3.60E-02 | 15_Quies | ||
| 5mC | cg24646067 | 5 | 87,812,057 | IGR | Open sea | −0.08 | 2.00E-07 | 3.60E-02 | 15_Quies | ||
| 5mC | cg27312312 | 14 | 56,046,001 | KTN1 | TSS1500 | Shore | 0.04 | 2.08E-07 | 3.60E-02 | 1_TssA | Microtubulue-associated protein |
| 5mC | cg16096172 | 6 | 46,924,482 | IGR | Open sea | 0.03 | 2.46E-07 | 3.60E-02 | 15_Quies |
Differentially methylated probes (FDR < 0.05) in the 5-methylcytosine (5mC) fraction. Probe ID Illumina probe ID, Chr chromosome, Position chromosomal position, chromHMM ChromHMM [40] data for the dorsolateral prefrontal cortex; 5_TxWk weak transcription activity, 15_Quies quiescent transcription, 1_TssA active TSS