Table 4.
Comparison of lipids and fatty acids with significant correlation with age among age groups
| 50 = < Age < 65 | 65 = < Age < 80 | 80 = < Age | ||
|---|---|---|---|---|
| n = 32 | n = 91 | n = 68 | p | |
| Age (m ± SD) years | 57.8 ± 4.1 | 72.3 ± 4.3 | 85.2 ± 4.5 | |
| Lipids | ||||
| T-CHO (m ± SD) mg/dl | 213.9 ± 42.9 | 203.7 ± 41.2 | 197.9 ± 36.9 | ns |
| TG (MD, IQR) mg/dl | 145.5, 65.5–217.8 ab | 92, 69–134 a | 92, 69–116 b | 0.0118 |
| Saturated Fatty Acids | ||||
| LaA (C12:0) (MD, IQR) μg/ml | 1.65, 0.8–3.65 | 1,2, 0.7–2.4 | 1.1, 0.7–1.78 | ns |
| MyA (C14:0) (MD, IQR) μg/ml | 21.9, 14.7–38.1 | 17.6, 13.8–27.2 | 17.5, 12.9–23.9 | ns |
| PA (C16:0) (MD, IQR) μg/ml | 763.9, 666.9–960.5 ac | 678.8, 580.7–828.7 a | 647.7, 577.1–735.6 c | 0.001 |
| StA (C18:0) (MD, IQR) μg/ml | 222.1, 196.6–258.8 bc | 207.4, 175.1–241.1 b | 185, 165.9–215.3 c | 0.001 |
| n-9 Monounsaturated Fatty Acid | ||||
| OlA (C18:1) (MD, IQR) μg/ml | 718.2, 614.9–863.3 bd | 604.8, 515.8–723.6 ab | 550.3, 494.0–644.6 ad | < 0.0001 |
| OlA (C18:1) (m ± SD) % | 22.3 ± 2.4 b | 21.3 ± 2.4 a | 20.7 ± 2.5 ab | 0.0046 |
| n-6 Polyunsaturated Fatty Acids | ||||
| LiA (C18:2) (MD, IQR) μg/ml | 882.4, 783.3–1003.8 d | 826.2, 692.9–957.4 c | 697.4, 636.2–845.5 cd | < 0.0001 |
| DGLA (C20:3) (MD, IQR) μg/ml | 35.6, 26.9–46.7 ac | 28.7, 21.6–36.5 a,a2 | 25.3, 19.7–31.2 a2,c | 0.0006 |
| AA (C20:4) (MD, IQR) μg/ml | 156.6, 144.1–198.2 ab | 144.7, 122.1–169.9 a | 140.6, 120–162.8 b | 0.0168 |
| DGLA (C20:3) (m ± SD) % | 1.1 ± 0.5 | 0.99 ± 0.29 | 0.96 ± 0.26 | ns |
| n-3 Polyunsaturated Fatty Acids | ||||
| AlA (C18:3) (MD, IQR) μg/ml | 23.1, 18.0–31.2 b | 23, 16.3–32.6 b2 | 18.4, 13.9–23.5 b,b2 | 0.0026 |
| EPA (C20:5) (MD, IQR) % | 1.535, 0.843–2.71 ab | 2.11, 1.54–3.15 a | 2.47, 1.77–3.54 b | 0.0048 |
| DHA (C22:6) (m ± SD) % | 3.88 ± 1.34 bd | 4.58 ± 1.36 b,b2 | 5.14 ± 1.18 b2,d | < 0.0001 |
| EPA / AA ratio (MD, IQR) | 0.325, 0.185–0.525 ab | 0.46, 0.34–0.6 a | 0.48, 0.353–0.718 b | 0.0115 |
| n-6 / n-3 ratio (MD, IQR) | 4.84, 3.693–7.598 b | 4.36, 3.42–5.46 a | 3.765, 3.00–4.595 ab | 0.0036 |
m Mean, SD Standard deviation, MD Median, IQR Interquartile range, % Weight percent of fatty acids, T-CHO Total cholesterol, TG Triglyceride, p Probability, a,a2: < 0.05, b,b2: < 0.01, c: < 0.001, d:< 0.0001, LaA Lauric acid, MyA Myristic acid, PA Palmitic acid, StA Stearic acid, OlA Oleic acid, LiA Linoleic acid, DGLA Dihomogammalinolenic acid, AA Arachidonic acid, ALA Alpha-linolenic acid, EPA Eicosapentaenoic acid, DHA Docosahexaenoic acid, EPA Eicosapentaenoic acid, AA Arachidonic acid, n-6 n-6 polyunsaturated fatty acids, n-3 n-3 polyunsaturated fatty acids,