Fig. 4.

Caveolin-1 is important for STAT3 activation in LPS-primed macrophages. (A,B) Representative western blot (A) and its densitometric analysis (B) of levels of active, i.e. phosphorylated STAT3 (p-STAT3) in untreated and LPS-primed macrophages derived from wild-type (WT) or caveolin-1^−/− mice stimulated with P2X7 receptor agonists (500 µM ATP or 100 µM Bz-ATP). Data are expressed as mean±s.e.m. of three independent experiments. *P<0.05 compared with the unstimulated control group. ^#P<0.05 when comparing WT with caveolin-1^−/− animals. ND, not detectable.