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. 2020 Mar 10;15(3):e0229850. doi: 10.1371/journal.pone.0229850

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© 2020 Campos et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — (A and B) Pharmacokinetic parameters observed in (A) blood (red circles) and (B) CSF (blue squares) after repeated 10mg/kg i.v. injections (arrows) of sFab OX26-NEP in cisterna magna cannulated rats (N = 3). (C and D) Aβ₄₀ levels measured in (C) blood plasma (red circles) and (D) CSF (blue squares).