Table 2. Comparison of 2D ADC measurement for treatment response of osteosarcoma.
| Parameters | Poor responder | Good responder | P |
|---|---|---|---|
| Pretreatment 2D ADCminimum | n = 9 | n = 2 | |
| Reader 1 | 870 [795;956] | 999 [870;1127] | 0.555 |
| Reader 2 | 955 [813;1268] | 939 [765;1112] | 0.813 |
| Pretreatment 2D ADCmean | n = 9 | n = 2 | |
| Reader 1 | 1130 [1065;1426] | 1180 [1011;1349] | 0.478 |
| Reader 2 | 1179 [1076;1585] | 1248 [1001;1495] | 0.637 |
| Posttreatment 2D ADCminimum | n = 13 | n = 4 | |
| Reader 1 | 1195 [1017;1384] | 1613 [1575;1751] | 0.024* |
| Reader 2 | 1099 [998;1481] | 1610 [1531;1656] | 0.089 |
| Posttreatment 2D ADCmean | n = 13 | n = 4 | |
| Reader 1 | 1439 [1232;1968] | 2151 [2081;2426] | 0.017* |
| Reader 2 | 1395 [1311;1964] | 2025 [1843;2182] | 0.089 |
| Percent change 2D ADCminimum | n = 9 | n = 2 | |
| Reader 1 | 30 [17;38] | 60 [44;77] | 0.099 |
| Reader 2 | 19 [-3;21] | 72 [51;93] | 0.034* |
| Percent change 2D ADCmean | n = 9 | n = 2 | |
| Reader 1 | 10 [8;28] | 80 [54;106] | 0.034* |
| Reader 2 | 9 [-2;23] | 55 [18;92] | 0.239 |
2D ADC, apparent diffusion coefficient values derived from single-section regions of interest.
*indicates statistical significance.