Table 5. Diagnostic performances of 3D ADC measurement for treatment response.
Parameters | Cutoff | Sensitivity | Specificity | AUC |
---|---|---|---|---|
Pretreatment 3D ADCmean | >943.24 | 89% | 50% | 0.667 |
Pretreatment 3D ADCskewness | ≤1.45 | 89% | 50% | 0.556 |
Pretreatment 3D ADCkurtosis | ≤6.33 | 89% | 50% | 0.611 |
Posttreatment 3D ADCmean | ≤2039.17 | 85% | 50% | 0.846* |
Posttreatment 3D ADCskewness | >-0.82 | 85% | 100% | 0.904* |
Posttreatment 3D ADCkurtosis | ≤4.9 | 77% | 75% | 0.692 |
Percent change 3D ADCmean | ≤45.1 | 89% | 50% | 0.889* |
Percent change 3D ADCskewness | >-153.65 | 100% | 50% | 0.500 |
Percent change 3D ADCkurtosis | ≤39.43 | 100% | 50% | 0.611 |
3D ADC, apparent diffusion coefficient values derived from whole-tumor volume.
AUC, areas under the curve.
*indicates statistical significance.