Table 2.
Effect of Tumor Size on Disease-Free Survival and Overall Survival in Patients with Triple Negative Breast Cancer
| Tumor Size | T1 (n=111) | T2 (n=84) | T3, T4 (n=19) | P value |
|---|---|---|---|---|
| Age at diagnosis (year; mean {SD}) | 67.6 (10.7) | 63.2 (12.7) v T1, p=0.010 |
64.5 (14.0) | 0.038 |
| Radiation technique (n) | ||||
| IMRT | 53/111 | 39/84 | 7/19 | |
| 3DCRT | 58/111 | 45/84 | 12/19 | |
| Fractionation (n) | ||||
| Conventional | 37/109 | 26/84 | 7/19 | |
| Hypofractionated | 72/109 | 58/84 | 12/19 | |
| p=0.0001a | p=0.0001a | p=0.194a | ||
| Disease-free survival (months; mean {SD}) | 106.5 (39.88) | 107.3 (46.47) | 54.78 (46.55) | <0.0001b |
| Overall survival (months; mean {SD}) | 110.2 (39.88) | 108.4 (58.01) | 66.60 (44.68) | 0.0004b |
Notes: aCompared to conventional fractionation; bLogrank test.
Abbreviations: 3D CRT, 3-dimensional conformal radiotherapy; IMRT, intensity modulated radiotherapy.