Table 3.
Effect of Nodal Status on Disease-Free Survival and Overall Survival in Patients with Triple Negative Breast Cancer
| Nodal Status a | N0 (n=133) | N1 (n=47) | N2, N3 (n=31) | P value |
|---|---|---|---|---|
| Age at diagnosis (year; mean {SD}) | 66.9 (10.7) | 64.1 (14.7) | 61.5 (11.8) v N0, p=0.014 |
|
| Radiation technique (n) | ||||
| IMRT | 63/133 | 18/47 | 16/31 | |
| 3DCRT | 70/133) | 29/47 | 15/31 | |
| p=0.0386b | ||||
| Fractionation (n) | ||||
| Conventional | 41/130 | 19/46 | 20/31 | |
| Hypofractionated | 89/130 | 27/46 | 11/31 | |
| p=0.0001c | p=0.0413c | |||
| Disease-free survival (months; mean {SD}) | 109.3 (35.57) | 86.1 (39.86) | 64.82 (60.80) | <0.0001d |
| Overall survival (months; mean {SD}) | 110.4 (38.14) | 92.0 (34.14) | 94.12 (53.67) | 0.012d |
Notes: aThree subjects were NX status (regional lymph nodes could not be assessed [previously removed]); bCompared to IMRT; cCompared to conventional fractionation; dLogrank test.
Abbreviations: 3D CRT, 3-dimensional conformal radiotherapy; IMRT, intensity modulated radiotherapy.