Skip to main content
. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Exp Eye Res. 2019 Oct 4;189:107825. doi: 10.1016/j.exer.2019.107825

Fig. 7.

Fig. 7.

Renal pathology in BBS7−/− macaques Case 1 (4 years) and Case 2 (6 years). Compared with a normal control (A), kidneys of BBS7−/− macaques (D,G) were scarred with extensive parenchymal loss grossly. H&E stained sections of affected macaques (E,F,H,I) demonstrated loss of nephrons with replacement fibrosis, tubule atrophy and ectasia. Cystic tubules were lined with attenuated to hyperplastic epithelium (F,I) which occasionally formed micropapillary projections (I). These microscopic findings were not present in the normal control (B,C). Black scale bars represent 100 μm.